Technical Brief

May 2nd, 2022
Emerging SARS-CoV-2 Variants and Detection
by the Lucira COVID-19 Check It and All-In-One Test Kits

The Centers for Disease Control and Prevention (CDC) and the World Health Organization
(WHO) have highlighted two notable SARS-CoV-2 Variants of Concern
1, 2:

 

(1) Delta (also known as B.1.617.2, all sublineages) first detected in India,

 

(2) Omicron (also known as B.1.1.529, BA.1, BA.1.1, BA.2, BA.3, BA.4, BA.5 and XE) first detected in multiple countries

 

Additionally, five other variants are under continued surveillance as Variants of Interest:

 

(3) Alpha (also known as B.1.1.7, all sublineages) first detected in the United Kingdom,

 

(4) Beta (also known as B.1.351, all sublineages) first detected in South Africa,

 

(5) Gamma (also known as P.1, all sublineages) first detected in Japan/Brazil,

 

(6) Lambda (also known as C.37, all sublineages) first detected in Peru,

 

(7) Mu (also known as B.1.621, all sublineages) first detected in Colombia

 

Lucira Health performs routine surveillance of emerging SARS-CoV-2 strains by periodically evaluating in silico reactivity against sequence databases. These evaluations have shown that these variants are reactive to the Lucira COVID-19 Check-It and All-In-One Test Kits. The Lucira Health assay targets two non-overlapping regions of the N gene. Hence the detection region is unaffected by the mutations in the spike protein of SARS-CoV-2 in the variant strains.

 

Lucira Health will continue to monitor the situation with emerging variants of SARS-CoV-2.

 

If you have any questions on the above, please reach out to Technical Support at
techsupport@lucirahealth.com.

 

1 https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html

2https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/