Technical Brief

January 11th, 2022
Emerging SARS-CoV-2 Variants
and Detection by the Lucira COVID-19 Check It and All-In-One Test Kits

The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have highlighted the emergence of five notable SARS-CoV-2 Variants of Concern:1, 2:

(1) Alpha (also known as B.1.1.7, all sublineages) first detected in the United Kingdom,

(2) Beta (also known as B.1.351, all sublineages) first detected in South Africa,

(3) Delta (also known as B.1.617.2, all sublineages) first detected in India,

(4) Gamma (also known as P.1, all sublineages) first detected in Japan/Brazil,

(5) Omicron (also known as B.1.1.529, all BA sublineages) first detected in multiple countries


Additionally, two variants have been identified to be highly prevalent:

(6) Lambda (also known as C.37, all sublineages) first detected in Peru,

(7) Mu (also known as B.1.621, all sublineages) first detected in Colombia


Lucira Health performs routine surveillance of emerging SARS-CoV-2 strains by periodically evaluating in silico reactivity against sequence databases. These evaluations have shown that these variants are reactive to the Lucira COVID-19 Check-It and All-In-One Test Kits. The Lucira Health assay targets two non-overlapping regions of the N gene. Hence the detection region is unaffected by the mutations in the spike protein of SARS-CoV-2 in the variant strains.


Lucira Health will continue to monitor the situation with emerging variants of SARS-CoV-2.


If you have any questions on the above, please reach out to Technical Support at